学习经历、社会兼职及获奖情况

2010年9月-2014年7月  赤峰学院       生物技术                          本科

2014年9月-2017年7月  塔里木大学   生物化学与分子生物学  硕士研究生

2018年9月-2023年1月  江南大学       发酵工程                          博士研究生

2023年1月-2025年2月  江南大学       食品科学学院                  博士后

2025年7月至今 宁夏大学 生命科学学院 教师

获奖情况：2023年江苏省卓越博士后计划、2023年度国家资助博士后研究人员计划B档

研究领域

1）微生物代谢工程和合成生物学强化微生物合成高值产品相关研究;

2）宁夏特色微生物挖掘、利用和种质资源库的构建。

代表性研究成果

(1)Li D, Deng ZW, Hou XD, et al. Structural insight into the catalytic mechanisms of an L-sorbosone dehydrogenase.Advanced Science, 2023. 10(30): e2301955. (SCI一区TOP，影响因子：15.1)

(2)Li D, Wang XL, Qin ZJ, et al. Combined engineering of L-sorbose dehydrogenase and fermentation optimization to increase 2-keto-L-gulonic acid production in Escherichia coli.Bioresource Technology, 2023. 372: 128672. (SCI一区TOP，影响因子：11.4)

(3)Li D, Liu L, Qin ZJ, et al. Combined evolutionary and metabolic engineering improve 2-keto-L-gulonic acid production inGluconobacter oxydansWSH-004.Bioresource Technology, 2022. 354: 127107. (SCI一区TOP，影响因子：11.889)

(4)Li D, Wang X, Huo L, et al. Computer-aided semi-rational design to enhance the activity of L-sorbosone dehydrogenase fromGluconobacter oxidansWSH-004.Journal of Agricultural and Food Chemistry, 2024. 72(19): 10995-11001. (SCI一区TOP，影响因子：5.7)

(5)Li D, Huo L, Jiang S, et al. Insights into the mechanism underlying the formation of covalent dimers of glucose/sorbosone dehydrogenase.Food Bioscience, 2024. 62: 105199. (SCI一区TOP，影响因子：4.8)

(6) Wu R,Li D, Chen Q, et al. Optimization of vanillin biosynthesis inEscherichia coliK12 MG1655 through metabolic engineering.Bioresource Technology, 2024. 411: 131189. (SCI一区TOP，影响因子：9.7)

(7) Liu S,Li D, Zhao X, et al. Production of food flavor and color by synthetic biology.Current Opinion in Food Science, 2024: 101168. (SCI一区TOP，影响因子：8.9)

(8) Zeng WZ,Li D, Zhang HH, et al. Multi-strategy integration improves 28-O-glucosylation of asiatic acid into asiatic acid monoglucoside.Food Bioscience, 2024. 61. (SCI一区TOP，影响因子：4.8)

(9) Wang XY,Li D, Qin ZJ, et al. CRISPR/Cpf1–FOKI-induced gene editing inGluconobacter oxydans.Synthetic and Systems Biotechnology, 2024. 9(2): 369-379. (SCI一区TOP，影响因子：4.4)

(10) Li G,Li D, Zeng WZ, et al. Efficient production of 2-keto-L-gulonic acid from D-glucose inGluconobacter oxydansATCC9937 by mining key enzyme and transporter.Bioresource Technology, 2023. 384: 129316. (SCI一区TOP，影响因子：11.4)

(11) Liu SK,Li D, Qin ZJ, et al.Enhancing Glycosylation of Flavonoids by Engineering the Uridine Diphosphate Glucose Supply inEscherichia coli.Journal of Agricultural and Food Chemistry, 2023. 71(46): 17842-17851. (SCI一区TOP，影响因子：6.1)

(12) Zhang Q, Wang XL, Zeng WZ, et al. De novo biosynthesis of carminic acid inSaccharomyces cerevisiae.Metabolic Engineering, 2023. 76: 50-62. (SCI一区TOP，影响因子：8.4)

(13) Chen Y,Li D, Shan XY, et al. Characterization of a sorbose oxidase involved in the biosynthesis of 2-keto-L-gulonic acid fromGluconobacter oxydansWSH-004.Process Biochemistry, 2022. 116: 1-7. (SCI三区，影响因子：4.885)